Our research focuses on developing next-generation high spatiotemporal resolution multi-dimensional single molecule dynamics imaging techniques and using them to explore the mystery of the complex biological system.

    Fully understanding the heterogenous interactions in the cellular process not only needs to locate the proteins with high precision but also needs to acquire the biomolecule dynamics with high temporal resolution. Real-time 3D single-particle tracking has emerged as a powerful tool for investigating dynamic biological interactions and has the potential to revolutionize the study of biological systems due to their high spatial and temporal resolution and high sensitivity. See an introduction of real-time single particle/molecule tracking for details.

Research topics

1. Developing  high spatiotemporal resolution multi-dimensional single molecule dynamics imaging techniques

2. Biomolecular interactions quantification 

3. AI-assisted biological nanoscopic imaging